ea0029s9.1 | The risk and benefits of tight glycaemic control | ICEECE2012
Gerstein Hertzel C.
Diabetes is a strong risk factor for cardiovascular (CV) events, and large epidemiologic studies have repeatedly shown that higher fasting or post-load glucose levels predict a higher incidence of CV events regardless of whether or not diabetes is present. In the UKPDS, targeting near-normal fasting glucose levels in newly diagnosed diabetes with a strategy starting with basal insulin or sulfonylurea reduced the 20-year risk of myocardial infarction and mortality by 15% and 13...